Open-field sex differences prior to puberty in rats

Prior exercise training attenuated Doxorubicin-induced hepatic oxidative stress in Wistar rats: Age-related differences

Introduction: Previous studies have confirmed the sidelong effects of Doxorubicin (DOX) on healthy tissues, but pretreatment effect of regular Aerobic exercise in restrain of hepatotoxicity induced by doxorubicin is not clear. The aim of this study was to investigate the pretreatment effect of regular aerobic exercise on hepatic oxidative stress induced with doxorubicin of Wistar rats in differ...

Sex differences in dental development in children with precocious puberty related to central nervous system lesions.

Forty-three children with precocious puberty related to central nervous system (CNS) lesions were examined. Plasma concentrations of estradiol in the females and testosterone in the males were obtained. Panoramic radiographs were used to assess dental root and crown development. All mandibular canines, premolars, and molars were included which could be visualized without apparent distortion. De...

Sex differences in forced-swim and open-field test behaviours after chronic administration of melatonin.

The effects of melatonin administered chronically on forced-swim test and open-field test behaviours were examined in male and female rats. The forced-swim test has been shown to be sensitive to all major classes of antidepressants and evidence indicates that melatonin possesses putative antidepressive properties. Male and female Long-Evans rats received either a regimen of chronic administrati...

Sex Differences in the Contribution of Puberty to Depression: the Role of Other-sex Relationship Stress By

Aged rats: sex differences and responses to chronic stress.

Cognitive, as well as physiological, sex differences exist in young adult rats under both basal conditions and following chronic stress; however, few studies have examined whether sex differences remain in aged subjects and whether responses to stress are altered. We compared aged male and female Fischer 344 rats (21.5 months at testing) without stress and when given 21 days of restraint for 6 ...